LYDIC -MR is a combination of the active ingredients diclofenac potassium, paracetamol, and chlorzoxazone. Diclofenac acts by attenuation of peripheral prostaglandin synthesis and marked anti-inflammatory properties. Paracetamol acts centrally and inhibits brain prostaglandin synthesis which may partly account for its well documented actively to reduce fever and induce analgesia. Chlorzoxazone being a centrally acting muscle relaxant relieves muscular spasms. The combination exerts a better pain control due to action on different pathways of pain.