Contract Manufacturer of TIZANIDINE HYDROCHLORIDE (Tablet, Capsules) Introduction Tizanidine HCl is categorized as an agonist of alpha2 adrenergic agonist prescribed as a muscle relaxant for spasticity management by presynaptic inhibition. It is a short-acting Product for temporarily relaxing muscle tone. Class Muscle Relaxer & 2 Adrenergic agonist Mechanism of action Tizanidine HCl is work to relax muscle spasm by interfering with the transmission of pain sensations (nerve impulses) that are sent to the brain through agonistically acting centrally at the alpha2 adrenergic receptor. Pharmacokinetics Absorption- absorbed orally Bound to plasma protein- Tizanidine-30% Half-life of Tizanidine- 2.5 hours Pharmacological uses Tizanidine hydrochloride is used for the spinal cord disease, Brain injury & disorders, Nerve disorders, acute low back pain, spasticity. Side effects of Tizanidine  Increased liver enzyme  Muscular weakness  Low blood pressure  Nausea  Sleepiness  Slow heartbeat  Hallucination, confusion & unusual thoughts  Burning or pain during urination Product interaction  Aciclovir, Amitriptyline & Amlodipine (increase serum concentration)  Benazepril, Captopril (its hypotensive activities increases)  Bunazosin (decrease vasoconstriction action)  Cholecalciferol Contraindicated in pregnant & breastfeeding women & patient with hypersensitivity. Dosage The recommended dose begins with a single dose per day & gradually it increases or as recommended by Doctor. We are the supplier of Nimesulide & Tizanidine & also a trader of Nimesulide & Tizanidine. * The following symptoms are suggestive & needs to be confirmed before promoting or coating anywhere & anybody whom so ever. Power2pharma.com & its parent company NEWS pharma Pvt. Ltd. is not responsible for its authenticity.

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